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Cystatin SA rabbit pAb
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ES4874
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Cystatin SA rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: CST2; Cystatin-SA; Cystatin-2; Cystatin-S5
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CST2. AA range:11-60
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 16kD
GeneID: 1470
Human Swiss-Prot No: P09228
Cellular localization: Secreted .
Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and seminal plasma. [provided by RefSeq, Jul 2008],