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Eme1 rabbit pAb
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ES4872
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Eme1 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: EME1; MMS4; Crossover junction endonuclease EME1; MMS4 homolog; hMMS4
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from Eme1 . at AA range: 250-330
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 65kD
GeneID: 146956
Human Swiss-Prot No: Q96AY2
Cellular localization: Nucleus, nucleolus . Recruited to regions of DNA damage in S-phase cells.
Background: This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],