PABP5 rabbit pAb

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PABP5 rabbit pAb

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ES4829

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	PABP5 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	PABPC5; PABP5; Polyadenylate-binding protein 5; PABP-5; Poly(A)-binding protein 5
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human PABPC5. AA range:184-233
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	43kD
GeneID:	140886
Human Swiss-Prot No:	Q96DU9
Cellular localization:	Cytoplasm .; [Isoform 2]: Mitochondrion matrix . Co-fractionates with mtDNA and co-immunoprecipitates with the mitochondrial poly(A) polymerase.
Background:	This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010],

Western blot analysis of lysates from K562 cells, using PABPC5 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from HeLa cells using PABPC5 antibody.
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).