NCoA-7 rabbit pAb

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NCoA-7 rabbit pAb

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ES4779

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	NCoA-7 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	NCOA7; ERAP140; ESNA1; Nbla00052; Nbla10993; Nuclear receptor coactivator 7; 140 kDa estrogen receptor-associated protein; Estrogen nuclear receptor coactivator 1
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human NCOA7. AA range:422-471
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	106kD
GeneID:	135112
Human Swiss-Prot No:	Q8NI08
Cellular localization:	Nucleus .
Background:	function:Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.,similarity:Belongs to the OXR1 family.,similarity:Contains 1 LysM repeat.,similarity:Contains 1 TLD domain.,subunit:Interacts with ESR1, ESR2A, ESR2B, THRB, PPARG and RARA in a ligand-inducible manner. Interacts with the heterodimer AHR-ARNT.,tissue specificity:Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.,

Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by i
Western blot analysis of lysates from LOVO, NIH/3T3, and RAW264.7 cells, using NCOA7 Antibody. The lane on the right is blocked with the synthesized peptide.