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ACTR-IC rabbit pAb
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ES4754
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ACTR-IC rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: ACVR1C; ALK7; Activin receptor type-1C; Activin receptor type IC; ACTR-IC; Activin receptor-like kinase 7; ALK-7
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human ACTR-1C. AA range:201-250
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 55kD
GeneID: 130399
Human Swiss-Prot No: Q8NER5
Cellular localization: Membrane ; Single-pass type I membrane protein .
Background: ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008],