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COL6A2 rabbit pAb
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ES4747
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Overview

Product name: COL6A2 rabbit pAb
Reactivity: Human;Mouse;Monkey
Alternative Names: COL6A2; Collagen alpha-2(VI) chain
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Collagen VI alpha2. AA range:691-740
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 109kD
GeneID: 1292
Human Swiss-Prot No: P12110
Cellular localization: Secreted, extracellular space, extracellular matrix . Membrane ; Peripheral membrane protein . Recruited on membranes by CSPG4.
Background: This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008],