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COL4A5 rabbit pAb
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ES4740
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50 µL $148.00
100 µL $248.00
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Overview

Product name: COL4A5 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: COL4A5; Collagen alpha-5(IV) chain
Source: Rabbit
Dilutions: WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Collagen IV alpha5. AA range:21-70
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 160kD
GeneID: 1287
Human Swiss-Prot No: P29400
Cellular localization: Secreted, extracellular space, extracellular matrix, basement membrane.
Background: This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010],