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AChRβ1 rabbit pAb
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ES4643
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50 µL $148.00
100 µL $248.00
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Overview

Product name: AChRβ1 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: CHRNB1; ACHRB; CHRNB; Acetylcholine receptor subunit beta
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CHRNB1. AA range:41-90
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 55kD
GeneID: 1140
Human Swiss-Prot No: P11230
Cellular localization: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Background: The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008],