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IRAK-M rabbit pAb
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ES4616
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50 µL $148.00
100 µL $248.00
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Overview

Product name: IRAK-M rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: IRAK3; Interleukin-1 receptor-associated kinase 3; IRAK-3; IL-1 receptor-associated kinase M; IRAK-M
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human IRAK3. AA range:491-540
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 68kD
GeneID: 11213
Human Swiss-Prot No: Q9Y616
Cellular localization: Cytoplasm . Nucleus . In dendritic cells, translocates into the nucleus upon IL33 stimulation. .
Background: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010],