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ADAMTS-7 rabbit pAb
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ES4607
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ADAMTS-7 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: ADAMTS7; A disintegrin and metalloproteinase with thrombospondin motifs 7; ADAM-TS 7; ADAM-TS7; ADAMTS-7; COMPase
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from ADAMTS-7 . at AA range: 150-230
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 110kD
GeneID: 11173
Human Swiss-Prot No: Q9UKP4
Cellular localization: Secreted, extracellular space, extracellular matrix . Also found associated with the external cell surface. .
Background: The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease. [provided by RefSeq, Feb 2016],