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Stonin-1 rabbit pAb
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ES4585
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Stonin-1 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: STON1; SALF; SBLF; STN1; Stonin-1; Stoned B-like factor
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human STON1. AA range:686-735
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 83kD
GeneID: 11037
Human Swiss-Prot No: Q9Y6Q2
Cellular localization: Cytoplasm . Membrane . Some fraction is membrane-associated.
Background: stonin 1(STON1) Homo sapiens Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of an N-terminal proline-rich domain, a central region of homology specific to the human stoned B-like proteins, and a C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes. Read-through transcription of this gene into the neighboring downstream gene, which encodes TFIIA-alpha/beta-like factor, generates a transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010],