LEKTI rabbit pAb

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LEKTI rabbit pAb

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ES4581

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	LEKTI rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	SPINK5; Serine protease inhibitor Kazal-type 5; Lympho-epithelial Kazal-type-related inhibitor; LEKTI
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human SPINK5. AA range:494-543
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	120kD
GeneID:	11005
Human Swiss-Prot No:	Q9NQ38
Cellular localization:	Secreted.
Background:	This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

Western Blot analysis of 3T3 cells using LEKTI Polyclonal Antibody
Western blot analysis of SPINK5 Antibody. The lane on the right is blocked with the SPINK5 peptide.
Western blot analysis of the lysates from COLO205 cells using SPINK5 antibody.
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).