PDE10A rabbit pAb

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PDE10A rabbit pAb

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ES4562

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	PDE10A rabbit pAb
Reactivity:	Human;Rat
Alternative Names:	PDE10A; cAMP and cAMP-inhibited cGMP 3'; 5'-cyclic phosphodiesterase 10A
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen:	The antiserum was produced against synthesized peptide derived from human PDE10A. AA range:21-70
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	75kD
GeneID:	10846
Human Swiss-Prot No:	Q9Y233
Cellular localization:	Cytoplasm, cytosol .
Background:	The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011],

Western Blot analysis of A549 cells using PDE10A Polyclonal Antibody
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).