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PDLIM5 rabbit pAb
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ES4520
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50 µL $148.00
100 µL $248.00
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Overview

Product name: PDLIM5 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: PDLIM5; ENH; L9; PDZ and LIM domain protein 5; Enigma homolog; Enigma-like PDZ and LIM domains protein
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human PDLIM5. AA range:208-257
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 64kD
GeneID: 10611
Human Swiss-Prot No: Q96HC4
Cellular localization: Cell junction, synapse, postsynaptic density . Cell junction, synapse, presynapse . Cell junction, synapse, postsynapse . Cytoplasm, cytosol . Detected both at presynaptic and postsynaptic sites, exclusively at excitatory synapses, but not inhibitory synapses, in hippocampal neurons. .
Background: This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012],