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Mad 4 rabbit pAb
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ES4518
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Mad 4 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: MXD4; BHLHC12; MAD4; Max dimerization protein 4; Max dimerizer 4; Class C basic helix-loop-helix protein 12; bHLHc12; Max-associated protein 4; Max-interacting transcriptional repressor MAD4
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MAD4. AA range:10-59
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 24kD
GeneID: 10608
Human Swiss-Prot No: Q14582
Cellular localization: Nucleus .
Background: This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008],