SLU7 rabbit pAb

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SLU7 rabbit pAb

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ES4507

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	SLU7 rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	SLU7; Pre-mRNA-splicing factor SLU7; hSlu7
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300
Immunogen:	The antiserum was produced against synthesized peptide derived from human SLU7. AA range:113-162
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	65kD
GeneID:	10569
Human Swiss-Prot No:	O95391
Cellular localization:	Nucleus . Nucleus speckle . Cytoplasm . Predominantly nuclear. Shuttling between the nucleus and the cytoplasm is regulated by the CCHC-type zinc finger. Upon UV-C stress stimulus, the nuclear concentration of the protein decreases, affecting alternative splicing. Translocates from the nucleus to the cytoplasm after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules. .
Background:	Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008],

Western Blot analysis of SH-SY5Y cells using SLU7 Polyclonal Antibody diluted at 1:1000
Western blot analysis of lysates from HeLa cells, using SLU7 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from HepG2 cells using SLU7 antibody.
Immunohistochemical analysis of paraffin-embedded human oophoroma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).