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C/EBP α (phospho Thr226) rabbit pAb
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ES4487
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50 µL $148.00
100 µL $248.00
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Overview

Product name: C/EBP α (phospho Thr226) rabbit pAb
Reactivity: Human;Mouse;Rat;Monkey
Alternative Names: CEBPA; CCAAT/enhancer-binding protein alpha; C/EBP alpha
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human C/EBP-alpha around the phosphorylation site of Thr226. AA range:192-241
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 42,also have 30kd isform
GeneID: 1050
Human Swiss-Prot No: P49715
Cellular localization: Nucleus .; [Isoform 4]: Nucleus, nucleolus .
Background: This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013],