Cdc42EP2 rabbit pAb

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Cdc42EP2 rabbit pAb

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ES4471

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	Cdc42EP2 rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	CDC42EP2; BORG1; CEP2; Cdc42 effector protein 2; Binder of Rho GTPases 1
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human BORG1. AA range:10-59
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	28kD
GeneID:	10435
Human Swiss-Prot No:	O14613
Cellular localization:	Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton .
Background:	CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011],

Western Blot analysis of K562 cells using Cdc42EP2 Polyclonal Antibody
Western blot analysis of lysates from K562 cells, using BORG1 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).