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SEMA3A rabbit pAb
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ES4466
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: SEMA3A rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: SEMA3A; SEMAD; Semaphorin-3A; Semaphorin III; Sema III
Source: Rabbit
Dilutions: WB 1:500-2000 ,Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human SEMA3A. AA range:688-737
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 89kD
GeneID: 10371
Human Swiss-Prot No: Q14563
Cellular localization: Secreted .
Background: This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. [provided by RefSeq, Jul 2008],