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Rag B rabbit pAb
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ES4464
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Rag B rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: RRAGB; Ras-related GTP-binding protein B; Rag B; RagB
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from Rag B . at AA range: 50-130
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 43kD
GeneID: 10325
Human Swiss-Prot No: Q5VZM2
Cellular localization: Cytoplasm . Lysosome .
Background: Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008],