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WAVE2 rabbit pAb
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ES4431
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50 µL $148.00
100 µL $248.00
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Overview

Product name: WAVE2 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: WASF2; WAVE2; Wiskott-Aldrich syndrome protein family member 2; WASP family protein member 2; Protein WAVE-2; Verprolin homology domain-containing protein 2
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human WASF2. AA range:141-190
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 55kD
GeneID: 10163
Human Swiss-Prot No: Q9Y6W5
Cellular localization: Cytoplasm, cytoskeleton . Cell projection, lamellipodium . Basolateral cell membrane . At the interface between the lamellipodial actin meshwork and the membrane. .
Background: This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011],