LI-cadherin rabbit pAb

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LI-cadherin rabbit pAb

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ES4430

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	LI-cadherin rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	CDH17; Cadherin-17; Intestinal peptide-associated transporter HPT-1; Liver-intestine cadherin; LI-cadherin
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human CDH17. AA range:341-390
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	99kD
GeneID:	1015
Human Swiss-Prot No:	Q12864
Cellular localization:	Cell membrane ; Single-pass type I membrane protein .
Background:	This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009],

Western Blot analysis of Jurkat cells using LI-cadherin Polyclonal Antibody
Immunofluorescence analysis of HeLa cells, using CDH17 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from Jurkat and HUVEC cells, using CDH17 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).