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OB-cadherin rabbit pAb
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ES4422
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50 µL $148.00
100 µL $248.00
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Overview

Product name: OB-cadherin rabbit pAb
Reactivity: Human;Mouse
Alternative Names: CDH11; Cadherin-11; OSF-4; Osteoblast cadherin; OB-cadherin
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CDH11. AA range:421-470
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 85kD
GeneID: 1009
Human Swiss-Prot No: P55287
Cellular localization: Cell membrane; Single-pass type I membrane protein.
Background: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008],