Products

TH (phospho Ser8) rabbit pAb
One-click to copy product information
ES4390
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: TH (phospho Ser8) rabbit pAb
Reactivity: Rat
Alternative Names: TH; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from mouse Tyrosine Hydroxylase around the phosphorylation site of Ser8. AA range:2-51
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 62kD
Background: The tyrosine hydroxylase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.