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GDF-3 rabbit pAb
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ES4373
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50 µL $148.00
100 µL $248.00
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Overview

Product name: GDF-3 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: GDF3; Growth/differentiation factor 3; GDF-3
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 41kD
GeneID: 9573
Human Swiss-Prot No: Q9NR23
Cellular localization: Secreted . Cytoplasm . Mainly accumulated in the cytoplasm. .
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],