Products

Ron α rabbit pAb
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ES4339
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: Ron α rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: MST1R; PTK8; RON; Macrophage-stimulating protein receptor; MSP receptor; CDw136; Protein-tyrosine kinase 8; p185-Ron; CD136
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human MST1R. AA range:31-80
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 150kD
GeneID: 4486
Human Swiss-Prot No: Q04912
Cellular localization: Membrane; Single-pass type I membrane protein.
Background: This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016],