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AID rabbit pAb
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ES4296
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50 µL $148.00
100 µL $248.00
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Overview

Product name: AID rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: AICDA; AID; Activation-induced cytidine deaminase; Cytidine aminohydrolase
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human AICDA. AA range:81-130
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 24kD
GeneID: 57379
Human Swiss-Prot No: Q9GZX7
Cellular localization: Nucleus . Cytoplasm . Predominantly cytoplasmic (PubMed:21385873). In the presence of MCM3AP/GANP, relocalizes to the nucleus (By similarity). .
Background: This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009],