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ApoC-III rabbit pAb
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ES4280
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ApoC-III rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: APOC3; Apolipoprotein C-III; Apo-CIII; ApoC-III; Apolipoprotein C3
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human APOC3. AA range:46-95
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 11kD
GeneID: 345
Human Swiss-Prot No: P02656
Cellular localization: Secreted .
Background: Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia. [provided by RefSeq, Jul 2008],