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Neurotensin rabbit pAb
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ES4265
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Overview

Product name: Neurotensin rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: NTS; Neurotensin/neuromedin N
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human NTS. AA range:121-170
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 20kD
GeneID: 4922
Human Swiss-Prot No: P30990
Cellular localization: Secreted. Cytoplasmic vesicle, secretory vesicle. Packaged within secretory vesicles.
Background: This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014],