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EKLF rabbit pAb
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ES4155
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50 µL $148.00
100 µL $248.00
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Overview

Product name: EKLF rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: KLF1; EKLF; Krueppel-like factor 1; Erythroid krueppel-like transcription factor; EKLF
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human KLF1 around the non-acetylation site of Lys274. AA range:231-280
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 38kD
GeneID: 10661
Human Swiss-Prot No: Q13351
Cellular localization: Nucleus . Colocalizes with SUMO1 in nuclear speckles. .
Background: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009],