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CD169 rabbit pAb
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ES4129
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50 µL $148.00
100 µL $248.00
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Overview

Product name: CD169 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: SIGLEC1; SN; Sialoadhesin; Sialic acid-binding Ig-like lectin 1; Siglec-1; CD169
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human SIGLEC1. AA range:1321-1370
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 190kD
GeneID: 6614
Human Swiss-Prot No: Q9BZZ2
Cellular localization: [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
Background: This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008],