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Cytokeratin 19 rabbit pAb
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ES4079
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Cytokeratin 19 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: KRT19; Keratin, type I cytoskeletal 19; Cytokeratin-19; CK-19; Keratin-19; K19
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human KRT19. AA range:321-370
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 44kD
GeneID: 3880
Human Swiss-Prot No: P08727
Cellular localization: intermediate filament,plasma membrane,dystrophin-associated glycoprotein complex,Z disc,sarcolemma,costamere,extracellular exosome,cell periphery,terminal web,
Background: The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008],