Products

Protein C rabbit pAb
One-click to copy product information
ES3951
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: Protein C rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: PROC; Vitamin K-dependent protein C; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human PROC. AA range:181-230
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 52kD
GeneID: 5624
Human Swiss-Prot No: P04070
Cellular localization: Secreted . Golgi apparatus . Endoplasmic reticulum .
Background: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009],