ET-1 rabbit pAb

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ET-1 rabbit pAb

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ES3877

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	ET-1 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	EDN1; Endothelin-1; Preproendothelin-1; PPET1
Source:	Rabbit
Dilutions:	IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	25kD
GeneID:	1906
Human Swiss-Prot No:	P05305
Cellular localization:	Secreted.
Background:	This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

Western Blot analysis of mouse lung cells using ET-1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
Western blot analysis of lysate from mouse lung, using EDN1 Antibody.
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).