Products

Chymase rabbit pAb
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ES3853
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: Chymase rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: CMA1; CYH; CYM; Chymase; Alpha-chymase; Mast cell protease I
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from the Internal region of human Chymase.
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 27kD
GeneID: 1215
Human Swiss-Prot No: P23946
Cellular localization: Secreted. Cytoplasmic granule. Mast cell granules.
Background: chymase 1(CMA1) Homo sapiens This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015],