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UBE4A rabbit pAb
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ES3810
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50 µL $148.00
100 µL $248.00
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Overview

Product name: UBE4A rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: UBE4A; KIAA0126; Ubiquitin conjugation factor E4 A
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from the N-terminal region of human UBE4A.
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 122kD
GeneID: 9354
Human Swiss-Prot No: Q14139
Cellular localization: Cytoplasm .
Background: This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011],