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SV2C rabbit pAb
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ES3807
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50 µL $148.00
100 µL $248.00
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Overview

Product name: SV2C rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: SV2C; KIAA1054; Synaptic vesicle glycoprotein 2C
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from the Internal region of human SV2C.
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 82kD
GeneID: 22987
Human Swiss-Prot No: Q496J9
Cellular localization: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein . Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas. .
Background: function:Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.,PTM:N-glycosylated.,similarity:Belongs to the major facilitator superfamily.,subcellular location:Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.,subunit:Interacts with SYT1 in a calcium-dependent manner.,