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APLP-1 rabbit pAb
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ES3788
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50 µL $148.00
100 µL $248.00
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Overview

Product name: APLP-1 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: APLP1; Amyloid-like protein 1; APLP; APLP-1
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from APLP-1 . at AA range: 360-440
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 72kD
GeneID: 333
Human Swiss-Prot No: P51693
Cellular localization: Cell membrane; Single-pass type I membrane protein.; [C30]: Cytoplasm. C-terminally processed in the Golgi complex.
Background: This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],