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EEA1 rabbit pAb
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ES3758
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50 µL $148.00
100 µL $248.00
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Overview

Product name: EEA1 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: EEA1; ZFYVE2; Early endosome antigen 1; Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human EEA1. AA range:205-254
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 162kD
GeneID: 8411
Human Swiss-Prot No: Q15075
Cellular localization: Cytoplasm. Early endosome membrane; Peripheral membrane protein.
Background: disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.,