MCAD rabbit pAb

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MCAD rabbit pAb

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ES3754

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	MCAD rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	ACADM; Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; MCAD
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300
Immunogen:	The antiserum was produced against synthesized peptide derived from human MCAD. AA range:134-183
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	46kD
GeneID:	34
Human Swiss-Prot No:	P11310
Cellular localization:	Mitochondrion matrix .
Background:	This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Western Blot analysis of extracts from A549 cells, using MCAD Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
Western blot analysis of lysates from HeLa cells, using MCAD antibody.
Immunohistochemical analysis of paraffin-embedded human uterus. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).