UBE3C rabbit pAb

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UBE3C rabbit pAb

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ES3667

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	UBE3C rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	UBE3C; KIAA0010; KIAA10; Ubiquitin-protein ligase E3C; HectH2
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	Synthesized peptide derived from the Internal region of human UBE3C.
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	125kD
GeneID:	148581
Human Swiss-Prot No:	Q15386
Cellular localization:	proteasome complex,intracellular,nucleus,cytoplasm,
Background:	function:E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.,miscellaneous:A cysteine residue is required for ubiquitin-thioester formation.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 1 IQ domain.,subunit:Interacts with 26S proteasomes. Binds CAND2.,tissue specificity:Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas.,

Western Blot analysis of various cells using UBE3C Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Western Blot analysis of HuvEc cells using UBE3C Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).