TLK1 rabbit pAb

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TLK1 rabbit pAb

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ES3616

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	TLK1 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	TLK1; KIAA0137; Serine/threonine-protein kinase tousled-like 1; PKU-beta; Tousled-like kinase 1
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen:	The antiserum was produced against synthesized peptide derived from human TLK1. AA range:201-250
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	87kD
GeneID:	9874
Human Swiss-Prot No:	Q9UKI8
Cellular localization:	Nucleus .
Background:	Serine/threonine-protein kinase tousled-like 1 encoded by TLK1 is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.

Western Blot analysis of various cells using TLK1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
Western blot analysis of TLK1 Antibody. The lane on the right is blocked with the TLK1 peptide.
Immunohistochemical analysis of paraffin-embedded human oophoroma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).