PDE4C rabbit pAb

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PDE4C rabbit pAb

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ES3163

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	PDE4C rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	PDE4C; DPDE1; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4C; DPDE1; PDE21
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen:	The antiserum was produced against synthesized peptide derived from human PDE4C. AA range:291-340
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	80kD
GeneID:	5143
Human Swiss-Prot No:	Q08493
Cellular localization:	Cell projection, cilium .
Background:	The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011],

Western Blot analysis of various cells using PDE4C Polyclonal Antibody
Western blot analysis of PDE4C Antibody. The lane on the right is blocked with the PDE4C peptide.
Western blot analysis of the lysates from HeLa cells using PDE4C antibody.
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).