MRP3 rabbit pAb

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MRP3 rabbit pAb

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ES2824

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	MRP3 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	ABCC3; CMOAT2; MLP2; MRP3; Canalicular multispecific organic anion transporter 2; ATP-binding cassette sub-family C member 3; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-associated protein 3
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300
Immunogen:	The antiserum was produced against synthesized peptide derived from human ABCC3. AA range:971-1020
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	170kD
GeneID:	8714
Human Swiss-Prot No:	O15438
Cellular localization:	Basolateral cell membrane ; Multi-pass membrane protein .
Background:	The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using MRP3 Polyclonal Antibody diluted at 1:2000
Western Blot analysis of HepG2 cells using MRP3 Polyclonal Antibody diluted at 1:2000
Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).