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LOK rabbit pAb
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ES2721
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50 µL $148.00
100 µL $248.00
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Overview

Product name: LOK rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: STK10; LOK; Serine/threonine-protein kinase 10; Lymphocyte-oriented kinase
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human STK10. AA range:491-540
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 120kD
GeneID: 6793
Human Swiss-Prot No: O94804
Cellular localization: Cell membrane ; Peripheral membrane protein .
Background: This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008],