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IL-2 rabbit pAb
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ES2611
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50 µL $148.00
100 µL $248.00
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Overview

Product name: IL-2 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: IL2; Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human IL-2. AA range:16-65
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 15kD
GeneID: 3558
Human Swiss-Prot No: P60568
Cellular localization: Secreted.
Background: The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008],