Ikaros 3 rabbit pAb

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Ikaros 3 rabbit pAb

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ES2599

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	Ikaros 3 rabbit pAb
Reactivity:	Human;Mouse
Alternative Names:	IKZF3; ZNFN1A3; Zinc finger protein Aiolos; Ikaros family zinc finger protein 3
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human IKZF3. AA range:361-410
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	62kD
GeneID:	22806
Human Swiss-Prot No:	Q9UKT9
Cellular localization:	Nucleus . Cytoplasm .; [Isoform 1]: Nucleus .; [Isoform 3]: Nucleus .; [Isoform 11]: Nucleus .; [Isoform 14]: Nucleus . Cytoplasm .; [Isoform 12]: Cytoplasm .
Background:	This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012],

Western Blot analysis of various cells using Ikaros 3 Polyclonal Antibody diluted at 1:1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Western blot analysis of lysates from COLO cells, using IKZF3 Antibody. The lane on the right is blocked with the synthesized peptide.