GRK 5 rabbit pAb

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GRK 5 rabbit pAb

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ES2480

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	GRK 5 rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	GRK5; GPRK5; G protein-coupled receptor kinase 5; G protein-coupled receptor kinase GRK5
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human GRK5. AA range:351-400
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	68kD
GeneID:	2869
Human Swiss-Prot No:	P34947
Cellular localization:	Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Predominantly localized at the plasma membrane; targeted to the cell surface through the interaction with phospholipids. Nucleus localization is regulated in a GPCR and Ca(2+)/calmodulin-dependent fashion.
Background:	This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using GRK 5 Polyclonal Antibody
Western Blot analysis of COLO205 cells using GRK 5 Polyclonal Antibody
Western blot analysis of lysates from HeLa, HepG2, and HUVEC cells, using GRK5 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).