GRK 3 rabbit pAb

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GRK 3 rabbit pAb

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ES2479

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	GRK 3 rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	ADRBK2; BARK2; GRK3; Beta-adrenergic receptor kinase 2; Beta-ARK-2; G-protein-coupled receptor kinase 3
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human GRK3. AA range:361-410
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	80kD
GeneID:	157
Human Swiss-Prot No:	P35626
Cellular localization:	Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse .
Background:	The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using GRK 3 Polyclonal Antibody diluted at 1:500
Western blot analysis of lysates from HepG2 and HeLa cells, using GRK3 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from K562 cells using GRK3 antibody.
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).