| Product name: |
GM2/GD2 synthase rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
B4GALNT1; GALGT; SIAT2; Beta-1; 4 N-acetylgalactosaminyltransferase 1; (N-acetylneuraminyl)-galactosylglucosylceramide; GM2/GD2 synthase; GalNAc-T |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human B4GALNT1. AA range:281-330 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
60kD |
| GeneID: |
2583 |
| Human Swiss-Prot No: |
Q00973 |
| Cellular localization: |
Golgi apparatus membrane ; Single-pass type II membrane protein . |
| Background: |
beta-1,4-N-acetyl-galactosaminyltransferase 1(B4GALNT1) Homo sapiens GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013], |
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